| Date | Home | Away | Result |
|---|---|---|---|
| 11/28/25 1:30 PM | Sporting Gijon | Andorra CF | 1-1 |
| 11/29/25 7:00 AM | AD Ceuta FC | Burgos CF | 1-0 |
| 11/29/25 9:15 AM | CyD Leonesa | FC Granada | 0-1 |
| 11/29/25 11:30 AM | Albacete Balompie | Deportivo La Coruna | 0-2 |
| 11/29/25 11:30 AM | UD Almeria | SD Huesca | 0-0 |
| 11/29/25 2:00 PM | Real Valladolid | FC Malaga | 1-1 |
| 11/30/25 7:00 AM | Real Saragossa | CD Leganes | 3-2 |
| 11/30/25 9:15 AM | Racing Santander | SD Eibar | 4-0 |
| 11/30/25 11:30 AM | CD Mirandes | Real Sociedad B | 1-0 |
| 11/30/25 11:30 AM | Cordoba CF | FC Cadiz | 1-2 |
| 11/30/25 2:00 PM | CD Castellon | UD Las Palmas | 1-0 |